You Never Have to Feel This Way Again
About Opioid Dependence
How opioids work:
When opioids enter the bloodstream, they attach to opioid receptors (called mu receptors) in the brain, stimulate the release of dopamine, and produce pleasurable feelings. After repeated use, some people can experience withdrawal symptoms and cravings—and can have a strong psychological desire to repeat the experience.
So two things are going on here: One, withdrawal is so severe your loved one seeks out more drug. And two, cravings for the pleasurable feelings of euphoria induced by taking the drug, drives repeated use.
Dopamine is released and pleasurable feelings (+) are produced
As the opioid leaves the receptors, pleasurable feelings subside and possible cravings and withdrawal symptoms (-) begin