Safe, Confidential, Home-Based Opiate Detoxification
SUBOXONE helps in three ways:
When SUBOXONE moves onto the opioid receptors in a dependent patient's brain, it does three important things.
First, by attaching to the brain's opioid receptors, SUBOXONE suppresses withdrawal symptoms and drug cravings.
Second, SUBOXONE attaches to the brain's receptors—so other opioids have difficulty attaching.
Finally, although all opioids slow down breathing, when SUBOXONE is taken alone and as directed, it has an upper limit on how much it affects breathing. This limitation, known as the "ceiling effect," is due to buprenorphine being a partial agonist. While full agonists (opioid painkillers, heroin, methadone) continue to slow breathing as a person takes more of the drug. This "ceiling effect" makes an overdose death from slowed breathing less likely, when buprenorphine is taken alone.
Even with this "ceiling effect" patients should avoid taking SUBOXONE while taking other sedatives, especially benzodiazepines unless specifically advised to do so by their doctor. This is because the effects of other sedatives may add to the sedating and respiratory depressant effects of buprenorphine, and the combination may be dangerous. Mixing buprenorphine with benzodiazepines for snorting or injection is especially dangerous. Patients being treated with buprenorphine should not use tranquilizers, antidepressants, or sedatives except under a doctor's orders, and they should avoid alcohol.